gene therapy :: essays research papers

factor Therapy is hope or disasterfor Human Being?&9674Introductiondesoxyribonucleic acid determines the placement of amino acids according to DNA sequences. A specific reach of amino acids composes a specific protein that plays the essential functions in the bodies. The defect of the constituent, however, results in producing wrong protein as a result, some part of the bodies ab rulerly work compared to that of some other public bodies. This is called ?gGenetic Disorder?h. The scientists studied about genetic distract and suggested an alternative for genetic disorder called ?gGene Therapy?h. Recently, gene therapy is useful to cure other diseases such as a rout outcer or other.(http//www.ornl.gov/sci/techresources/Human_Genome/medicine/genetherapy.shtmlhttp//www.asgt.org/ )&9674 bill of Gene TherapyDavid suffered from a rare inherited disease known as adenosine deaminase deficiency (ADA). He spent all his life in a germ-free plastic bubble, because gene causes a lack of enz yme that helps immune system to clamber disease from outside. In 1984, he received a bone nubble transplant. Unfortunately, cells from donator?fs marrow attacked his body. As a result, he was died after a family. This cause was a big issue at that time and scientists studied gene therapy to stop this bad event. In 1989, at first, W.French Anderson and a team at the National Institutes of Health gained permission for experiment to inject gene into valet de chambre beings. In 1900, at first, he use gene therapy to 4 year girl who suffered from adenosine deaminase deficiency (ADA). He extracted T- lymphocytes from her bloodstream and injected gene-corrected T lymphocytes to her with a approach pattern gene function for ADA then he repeated a few times more. After a year, she lives as a normal kid. Her treatment was successful. In 1991, 9 years old girl was applied to this gene therapy and her treatment was also successful.(http//www.frenchanderson.org/history/history.asp, Mapping our genes by Lois Wingerson, medical Dilemma by Margaret O.Hyde& Elizabeth H. Forsyth. M.D.)&9674Gene TherapyToday, basic theory of gene therapy is that normal gene is inserted into genome to replace disease caused gene. The gene by itself, however, is almost unsufferable to get the target cell. To deliver gene successfully, a carrier called sender is necessary and virus is good for delivering gene, because virus genetically approaches human genes. Virus, however, can have a potential toxic or respond a massive immune system. In fact, some people died because of that. For this reason, scientists tried to materialize replacement of virus as transmitter. The most common virus for vector is adenovirus that causes cold.